By Arthur M. Silverstein
Written via an immunologist, A historical past of Immunology traces the concept that of immunity from precedent days as much as the current day, analyzing how altering options and applied sciences have affected the process the technological know-how. It indicates how the personalities of scientists or even political and social elements prompted either idea and perform within the box. With attention-grabbing tales of clinical disputes and transferring clinical traits, each one bankruptcy examines a tremendous aspect of this self-discipline that has been so imperative to the advance of contemporary biomedicine. With its biographical dictionary of significant scientists and its lists of important discoveries and books, this quantity will give you the so much whole historic reference within the field.
- Written in a chic kind by means of long-time practising immunologist
- Discusses the altering theories and applied sciences that guided the field
- Tells of the intriguing disputes between widespread scientists
- Lists all of the vital discoveries and books within the field
- Explains intimately the various Nobel prize-winning contributions of immunologists
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Extra info for A History of Immunology, Second Edition
But the theory was taken up and pursued for a very long time by no less a figure than Paul Ehrlich. Ehrlich very early developed a keen interest in cancer, and as the result of experimental studies on the inability of certain tumors to grow in some animal species, and of the regression of tumors, he formulated a theory of tumor immunity to which he applied the term atrepsie. 45 Paying due respect to Pasteur’s depletion theory (which the Germans called Erscho¨pfung – exhaustion), Ehrlich suggested that just as bacteria might have special nutritional requirements, so also might different cancers.
Hist. Med. Allied Sci. 42:147, 1987) have speculated that in fact only a mild form of smallpox, akin to Variola minor, existed in Europe prior to the seventeenth century. Avicennae Arabum Medicorum Principis, Latin translation by Gerard of Cremona, Venice, 1608, Vol. II, pp. 72–73. , Plagues and Peoples, New York, Doubleday, 1976. Mercurialis, Hieronymus, De Morbis Puerorum, Basel, 1584, Book I, pp. 17–21. , The Adoption of Inoculation for Smallpox in England and France, Philadelphia, University of Pennsylvania Press, 1959, p.
With the rise of microscopy and anatomic pathology, purulent discharges were early associated with those inflammatory cells later named macrophages and microphages, and thus these cells were identified as the most obvious component of the deleterious inflammatory reaction. Moreover, it was generally thought by most pathologists of the era that phagocytic cells actually provided an admirable means of transport for infectious organisms in their dissemination throughout the body. It was in this context that Metchnikoff dared to suggest that the phagocytic cells, far from being harmful, in fact constitute a first line of defense in their ability to ingest and digest invading organisms.
A History of Immunology, Second Edition by Arthur M. Silverstein